pentobarbital will decrease the extent or outcome of pitolisant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Pitolisant exposure is decreased by fifty% if coadministered with potent CYP3A4 inducers.
pentobarbital decreases amounts of vandetanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration with strong CYP3A4 inducers; these drugs minimize exposure to vandetanib by up to forty%.
pentobarbital will reduce the level or outcome of verapamil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will reduce the level or result of parecoxib by impacting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Observe.
pentobarbital will reduce the level or outcome of fludrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lessen the extent or influence of cyclosporine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Check Carefully (1)pentobarbital will lessen the extent or effect of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or influence of etravirine by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep an eye on.
pentobarbital will lessen the extent or effect of cilostazol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Sufferers stabilized on corticosteroid therapy might have to have dosage changes if barbiturates are additional to or withdrawn from their dosage routine as a result of induction of hepatic microsomal enzymes by barbiturates
pentobarbital will minimize the level or impact of colchicine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the level or outcome of lapatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
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pentobarbital will reduce the level or result of read more doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.